Senior Research Support Assistant

Location
Brighton, East Sussex
Salary
£26,715 - £30,046 per annum
Posted
11 May 2021
Closes
31 May 2021
Contract Type
Contract
Hours
Full Time

UNIVERSITY OF BRIGHTON

Senior Research Support Assistant

School of Pharmacy and Biomolecular Sciences

Reference: SP5048-21-108-R

£26,715 - £30,046 per annum

Contract length: 24 months

We are currently seeking a Senior Research Support Assistant to work on an Engineering and Physical Sciences Research Council (EPSRC) project.

Increasing age is frequently associated with a build-up of faeces in the large bowel due to difficult, infrequent and incomplete emptying of the bowel (chronic constipation) as well as leaking of bowel contents (faecal incontinence). These are known as age-related bowel disorders. Over one third of the over 65-year-olds in the community and more than half of those in care homes will suffer these age-related bowel disorders. To the sufferer the symptoms can cause significant embarrassment, loss of dignity and quality of life. To the health service the cost of treating such conditions reached £1 billion in 2010. The number of people aged 65 and over will increase by more than 40% within 20 years, making this a major social and economic problem. Therefore, there needs to be an approach that allows for the early detection of predictive markers of age-related bowel disorders so that effective treatment can commence at an early stage, delaying/preventing the onset of the disorder and extending health span.

To resolve these challenges this project begins our journey. Within this project we will develop a novel in vivo electrochemical probe to monitor, understand and track age-related changes in the lower bowel function. The longer-term goal is to utilise the probe as a theragnostic device for the early detection of age-related lower bowel dysfunction. This will be achieved by the following objectives: (i) Convert the ex vivo electrochemical sensor into a drug-eluting in vivo probe (H.H.B. Hamzah et al, Anal. Chem., 2019, 91 (18), 12014-12020); (ii) Enhance the sensitivity and linear range of the in vivo probe to monitor contractions and mucosal signalling markers and (iii) Monitor in vivo age-related changes in lower bowel signalling and function.

You will provide research support to a project that is focused on the development of a drug-eluting in vivo electrochemical probe to monitor age-related lower bowel dysfunction. To be successful in this post, you should have:

•             A BSc in an aligned subject area associated with product design, engineering or physical sciences.

•             Experience in designing and making products using 3D printing.

•             Sufficient, up to date breadth or depth of specialist knowledge in sensing technologies that are utilised in healthcare.

•             Willingness to support characterisation studies of the probe using electrochemistry, as evaluation of the developed probe is a critical part of the proposal.

Informal enquires may be addressed to Professor Bhavik Patel at b.a.patel@brighton.ac.uk

Interview dates for the post will be held in June 2021.

Further details:

The University is committed to an inclusive environment which embraces equality and diversity in our working, learning, research and teaching environment. We particularly encourage applicants from a Black, Asian and Minority Ethnic (BAME) background because the University is underrepresented by BAME staff.

Closing date: Monday 31 May 2021.

Interview date: To be confirmed.

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